Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 12/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443122 | 0.90 | FNTA (0.37) | BDKRB1HPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9199570 | 0.87 | ALDH1A1 (0.39) | HPGDSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL3974805 | 0.86 | HPGD (0.37) | BDKRB1HPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2598198 | 0.84 | BDKRB1 (0.47) | BDKRB1HPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31722799 | 0.84 | BDKRB1 (0.47) | BDKRB1HPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9197854 | 0.84 | ALDH1A1 (0.39) | HPGDSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL3974372 | 0.83 | BDKRB1 (0.48) | BDKRB1HPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9287748 | 0.82 | ALDH1A1 (0.39) | BDKRB1HPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7009871 | 0.79 | HPGD (0.44) | BDKRB1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3976878 | 0.78 | ALDH1A1 (0.46) | BDKRB1HPGDSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425921-B1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0425921-A1 | Benzimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-05-08 | — | — | EP | disclosed |