Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 7/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199570 | 0.92 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2GAAAGTR1AGTR2 | |
| SCHEMBL9287748 | 0.91 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2GAAAGTR1AGTR2 | |
| SCHEMBL30443207 | 0.88 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAAAGTR1AGTR2 | |
| SCHEMBL3976878 | 0.88 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAAAGTR1AGTR2 | |
| SCHEMBL9196004 | 0.84 | BDKRB1 (0.42) | ALDH1A1SMN1; SMN2MAPTHPGDKDM4E | |
| SCHEMBL3974805 | 0.82 | HPGD (0.37) | ALDH1A1SMN1; SMN2MAPTHPGDKDM4E | |
| SCHEMBL7422107 | 0.80 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL31722799 | 0.79 | BDKRB1 (0.47) | ALDH1A1SMN1; SMN2MAPTHPGDKDM4E | |
| SCHEMBL2598198 | 0.79 | BDKRB1 (0.47) | ALDH1A1SMN1; SMN2MAPTHPGDKDM4E | |
| SCHEMBL29169639 | 0.79 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425921-B1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0425921-A1 | Benzimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-05-08 | — | — | EP | disclosed |