Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 8/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199124 | 0.97 | IGF1R (0.46) | HTR2BHTR3ADAOIGF1RALOX15 | |
| SCHEMBL6177760 | 0.92 | HTR2B (0.52) | HTR2BHTR3ADAOIGF1RALOX15 | |
| SCHEMBL6178657 | 0.88 | HTR2B (0.57) | HTR2BHTR3ADAOIGF1RALOX15 | |
| SCHEMBL9199296 | 0.87 | HTR2B (0.56) | HTR2BHTR3ADAOIGF1RALOX15 | |
| SCHEMBL6174221 | 0.83 | HTR2B (0.49) | HTR2BHTR3AIGF1RALOX15PGAM1 | |
| SCHEMBL6176274 | 0.83 | IDH1 (0.49) | HTR2BHTR3ADAOIGF1RALOX15 | |
| SCHEMBL6173771 | 0.81 | CNR1 (0.50) | HTR2BHTR2C | |
| SCHEMBL7449079 | 0.81 | HTR2B (0.44) | HTR2BHTR3ADAOIGF1RALOX15 | |
| SCHEMBL9195193 | 0.79 | HTR2B (0.45) | HTR2BHTR3ADAOIGF1RALOX15 | |
| SCHEMBL6174060 | 0.79 | HTR2B (0.44) | HTR2BHTR3ADAOIGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | disclosed |