Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857337 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2LOXL2CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL755467 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2LOXL2CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL5165440 | 0.80 | TSHR (0.55) | SMN1; SMN2LOXL2CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL30516320 | 0.80 | TSHR (0.55) | SMN1; SMN2LOXL2CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL28827921 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2LOXL2TSHRMEN1KMT2A | |
| SCHEMBL795457 | 0.78 | TSHR (0.60) | LOXL2CYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL4686240 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2LOXL2TSHRMEN1KMT2A | |
| SCHEMBL29457307 | 0.74 | LOXL2 (0.49) | SMN1; SMN2LOXL2CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL12556800 | 0.73 | CYP4F2 (0.51) | SMN1; SMN2LOXL2CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL9700206 | 0.73 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8127675-B2 | Lithographic printing plate precursor and lithographic printing method | FUJIFILM CORPORATION (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20100005989-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD | FUJIFILM CORPORATION | 2010-01-14 | — | — | US | disclosed |