Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL5806473 | 0.86 | ALDH1A1 (0.61) | — | |
| Isopropyl Alcohol SCHEMBL1289871 | 0.86 | ALDH1A1 (0.61) | — | |
| Isopropyl Alcohol SCHEMBL27792282 | 0.86 | — | — | |
| Monoethanolamine SCHEMBL2711586 | 0.83 | — | — | |
| Ethylene Glycol SCHEMBL28840991 | 0.82 | — | — | |
| Isobutane SCHEMBL9848780 | 0.82 | — | — | |
| Monoethanolamine SCHEMBL11451069 | 0.80 | TSHR (0.53) | — | |
| Cysteamine SCHEMBL8469638 | 0.80 | — | — | |
| Monoethanolamine SCHEMBL2177860 | 0.80 | — | — | |
| Propylene Glycol SCHEMBL7622439 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451940-B1 | Preparation of polymeric particles | TIOXIDE GROUP LTD (GB) | 1995-12-20 | — | — | EP | disclosed |
| US-5229209-A | Emulsion polymerization of unsaturated monomers, one with acid fulctionality; swelling polymeric particles with alkali to generate vesicles | TIOXIDE GROUP PLC (GB) | 1993-07-20 | — | — | US | disclosed |
| EP-0451940-A2 | Preparation of polymeric particles | TIOXIDE GROUP LIMITED (GB) | 1991-10-16 | — | — | EP | disclosed |