Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 17/20 | 0.53 |
| ▸ | GABRD | O14764 | 17/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 17/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 17/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 17/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 17/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 17/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 17/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 17/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 17/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 17/20 | 0.53 |
| ▸ | GABRE | P78334 | 17/20 | 0.53 |
| ▸ | GABRA6 | Q16445 | 17/20 | 0.53 |
| ▸ | GABRG1 | Q8N1C3 | 17/20 | 0.53 |
| ▸ | GABRG3 | Q99928 | 17/20 | 0.53 |
| ▸ | GABRQ | Q9UN88 | 17/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192998 | 0.93 | GABRB3 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9193470 | 0.88 | GABRB3 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9197601 | 0.82 | GABRB3 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9194007 | 0.82 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9196282 | 0.81 | GABRB3 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9193483 | 0.78 | GABRB3 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9704854 | 0.73 | GABRB3 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9704834 | 0.73 | GABRB3 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2834331 | 0.73 | GABRB3 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9192680 | 0.73 | GABRB3 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385809-B1 | Pesticidal 3-cyano-5-alkoxy-1-arylpyrazoles | RHONE POULENC AGROCHIMIE (FR) | 1995-07-05 | — | — | EP | disclosed |
| US-5079370-A | 1-arylpyrazoles | RHONE-POULENC AG COMPANY (US) | 1992-01-07 | — | — | US | disclosed |
| US-5047550-A | Pesticides | RHONE-POULENC AG CO. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0385809-A1 | Pesticidal 3-cyano-5-alkoxy-1-arylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1990-09-05 | — | — | EP | disclosed |
| US-4918085-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS, AND ANTIPROTOZOA AGENTS | RHONE-POULENC AG COMPANY (US) | 1990-04-17 | — | — | US | disclosed |