Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408602 | 0.82 | CYP19A1 (0.52) | CYP19A1EPHX2CACNA1FHTR1AADORA3 | |
| SCHEMBL9092356 | 0.72 | CYP19A1 (0.59) | CYP19A1EPHX2CACNA1FHTR1AADORA3 | |
| SCHEMBL9190835 | 0.71 | EPHX2 (0.59) | CYP19A1EPHX2CACNA1FHTR1AADORA3 | |
| SCHEMBL27692932 | 0.68 | HRH3 (0.45) | CYP19A1 | |
| SCHEMBL23126408 | 0.68 | EPHX2 (0.51) | CYP19A1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL8408610 | 0.67 | CYP19A1 (0.54) | CYP19A1EPHX2CACNA1FHTR1AADORA3 | |
| SCHEMBL8410909 | 0.67 | CYP19A1 (0.54) | CYP19A1EPHX2CACNA1FHTR1AADORA3 | |
| SCHEMBL5597463 | 0.67 | CYP19A1 (0.51) | CYP19A1CYP2C19 | |
| SCHEMBL8411269 | 0.64 | EPHX2 (0.58) | CYP19A1EPHX2CACNA1FHTR1AADORA3 | |
| SCHEMBL9191160 | 0.64 | CYP19A1 (0.48) | CYP19A1EPHX2CACNA1FHTR1AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674626-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | ORION-YHTYMÄ OY (FI) | 1995-10-04 | — | — | EP | claimed |
| EP-0674626-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | ORION-YHTYMÄ OY (FI) | 1995-10-04 | — | — | EP | disclosed |