Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204967 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KDM4ECYP3A4HPGDLMNA | |
| SCHEMBL8556308 | 0.99 | KDM4E (0.39) | ALDH1A1KDM4ECYP3A4HPGDLMNA | |
| SCHEMBL9200138 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4ECYP3A4HPGDLMNA | |
| SCHEMBL9203038 | 0.84 | KDM4E (0.35) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL9200064 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL9202296 | 0.76 | TSHR (0.46) | ALDH1A1KDM4ECYP3A4HPGDLMNA | |
| SCHEMBL9204956 | 0.75 | IKBKB (0.36) | ALDH1A1KDM4EHPGDMAPTIKBKB | |
| SCHEMBL7533737 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KDM4ECYP3A4HTTXDH | |
| SCHEMBL8556305 | 0.73 | KDM4E (0.31) | ALDH1A1KDM4EHPGDHTTMAPT | |
| SCHEMBL9204370 | 0.73 | PKM (0.46) | ALDH1A1KDM4EHPGDLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413226-B1 | [1,2,4]Triazo [1,5-a]pyridine | BASF AG (DE) | 1995-05-24 | — | — | EP | disclosed |
| US-5101028-A | Intermediates for dyes | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| EP-0413226-A2 | [1,2,4]Triazo [1,5-a]pyridine | BASF Aktiengesellschaft (DE) | 1991-02-20 | — | — | EP | disclosed |