SCHEMBL9196875

SCHEMBL9196875

CCOC(=O)c1cc(=O)n(-c2ccc(C(=O)O)cc2)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
MAPT P10636 2/20 0.62
KMT2A Q03164 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
KDM4E B2RXH2 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
GAA P10253 2/20 0.61
HTT P42858 2/20 0.61
MEN1 O00255 1/20 0.61
LMNA P02545 1/20 0.61
ALKBH5 Q6P6C2 10/20 0.52
HRH3 Q9Y5N1 1/20 0.49
HSP90AA1 P07900 1/20 0.45
HPGD P15428 1/20 0.45
CACNA1B Q00975 1/20 0.45
APBA1 Q02410 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5527198 0.88 ALDH1A1 (0.60) ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E
SCHEMBL2229684 0.88 MAPT (0.62) ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E
SCHEMBL11426196 0.85 KDM4E (0.71) ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E
SCHEMBL10755227 0.85 ALDH1A1 (0.57) ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E
SCHEMBL9324636 0.82 ALDH1A1 (0.54) ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E
SCHEMBL10405696 0.82 ALDH1A1 (0.54) ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E
SCHEMBL11643203 0.81 KDM4E (0.53) ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E
SCHEMBL10405697 0.81 ALDH1A1 (0.53) ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E
SCHEMBL11420145 0.81 ALDH1A1 (0.61) ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E
SCHEMBL10144737 0.80 MAPT (0.69) ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0430186-B1 Silver halide photographic light-sensitive materials FUJI PHOTO FILM CO LTD (JP) 1995-11-22 EP disclosed
US-5213957-A Oxonol dye with carboxy or sulfonamide group and indale ring FUJI PHOTO FILM CO., LTD. (JP) 1993-05-25 US disclosed
EP-0430186-A1 Silver halide photographic light-sensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1991-06-05 EP disclosed