Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.51 |
| ▸ | TACR2 | P21452 | 4/20 | 0.51 |
| ▸ | TACR1 | P25103 | 4/20 | 0.51 |
| ▸ | HPGDS | O60760 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197312 | 1.00 | L3MBTL1 (0.56) | L3MBTL1TAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL14856541 | 0.93 | TACR2 (0.56) | L3MBTL1TAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL14856306 | 0.93 | TACR2 (0.56) | L3MBTL1TAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL14856587 | 0.92 | RAB9A (0.61) | L3MBTL1TAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL20665160 | 0.88 | RAB9A (0.52) | TAS1R3TAS1R1TAS1R2TACR2TACR1 | |
| SCHEMBL4134276 | 0.80 | DDB1 (0.64) | HPGDSNPC1RAB9A | |
| SCHEMBL3730396 | 0.80 | DDB1 (0.64) | HPGDSNPC1RAB9A | |
| SCHEMBL2472548 | 0.78 | MEN1 (0.70) | L3MBTL1TAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL14856656 | 0.78 | RAB9A (0.66) | TACR2TACR1HPGDSSMN1; SMN2NPC1 | |
| SCHEMBL14856655 | 0.78 | RAB9A (0.66) | TACR2TACR1HPGDSSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519877-B1 | 3-Acylamino-2-pyrrolidinones as enhancers of the processes of learning and memory and pharmaceutical compositions containing same | SIGMA TAU IND FARMACEUTI (IT) | 1995-09-27 | — | — | EP | disclosed |
| EP-0519877-A1 | 3-Acylamino-2-pyrrolidinones as enhancers of the processes of learning and memory and pharmaceutical compositions containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1992-12-23 | — | — | EP | disclosed |