⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871779 | 0.79 | — | — | |
| SCHEMBL9254411 | 0.75 | MEN1 (0.33) | — | |
| SCHEMBL9199139 | 0.74 | — | — | |
| SCHEMBL29281624 | 0.73 | MEN1 (0.35) | — | |
| SCHEMBL10818983 | 0.73 | MEN1 (0.35) | — | |
| SCHEMBL10817404 | 0.72 | MEN1 (0.38) | — | |
| SCHEMBL10430384 | 0.71 | — | — | |
| SCHEMBL20955872 | 0.68 | MEN1 (0.31) | — | |
| SCHEMBL20955871 | 0.68 | MEN1 (0.31) | — | |
| SCHEMBL6097168 | 0.66 | TET3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360293-B1 | Process for the preparation of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines | LONZA AG (CH) | 1995-08-30 | — | — | EP | claimed |
| US-4990618-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-c]-pyridines | LONZA LTD. (CH) | 1991-02-05 | — | — | US | disclosed |
| US-4965359-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-C]-pyridines | LONZA LTD. (CH) | 1990-10-23 | — | — | US | disclosed |