⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197366 | 0.79 | — | — | |
| SCHEMBL9199899 | 0.77 | — | — | |
| SCHEMBL6596902 | 0.74 | — | — | |
| SCHEMBL22137379 | 0.69 | POLB (0.40) | — | |
| SCHEMBL10430384 | 0.67 | — | — | |
| SCHEMBL9199139 | 0.67 | — | — | |
| SCHEMBL517398 | 0.66 | CYP4F2 (0.40) | — | |
| SCHEMBL9732373 | 0.63 | CYP2C19 (0.34) | — | |
| SCHEMBL30301543 | 0.63 | NR1H2 (0.40) | — | |
| SCHEMBL4394294 | 0.62 | CTSK (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990618-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-c]-pyridines | LONZA LTD. (CH) | 1991-02-05 | — | — | US | disclosed |
| US-4965359-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-C]-pyridines | LONZA LTD. (CH) | 1990-10-23 | — | — | US | disclosed |