Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20955872 | 1.00 | MEN1 (0.31) | MEN1ALDH1A1POLBKMT2AGRIN1 | |
| SCHEMBL20980165 | 0.80 | POLB (0.41) | MEN1POLBKMT2A | |
| SCHEMBL23388889 | 0.78 | GRIN1 (0.34) | MEN1POLBKMT2AGRIN1GRIN2A | |
| SCHEMBL9254411 | 0.75 | MEN1 (0.33) | MEN1ALDH1A1POLBKMT2A | |
| SCHEMBL9800283 | 0.74 | GRIN1 (0.33) | POLBGRIN1GRIN2A | |
| SCHEMBL10818983 | 0.73 | MEN1 (0.35) | MEN1ALDH1A1POLBKMT2A | |
| SCHEMBL29281624 | 0.73 | MEN1 (0.35) | MEN1ALDH1A1POLBKMT2A | |
| SCHEMBL10817404 | 0.72 | MEN1 (0.38) | MEN1ALDH1A1POLBKMT2A | |
| SCHEMBL14378009 | 0.71 | MMP9 (0.32) | GRIN1GRIN2A | |
| SCHEMBL14378098 | 0.71 | GRIN1 (0.34) | GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3480190-B1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | CALIFORNIA INST OF TECHN (US) | 2023-01-04 | — | — | EP | disclosed |
| US-10745354-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-08-18 | — | — | US | disclosed |
| US-20200048201-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-02-13 | — | — | US | disclosed |
| US-10358422-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-23 | — | — | US | disclosed |
| US-20190135754-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2019-05-09 | — | — | US | disclosed |
| EP-3480190-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | California Institute of Technology (US) | 2019-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048201-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | LSS, COASY, ADH1A | MEN1 273/4885ALDH1A1 265/4885POLB 2421/4885 |
| US-20190135754-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | LSS, COASY, ADH1A | MEN1 273/4885ALDH1A1 265/4885POLB 2421/4885 |
| US-10745354-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | LSS, COASY, ADH1A | MEN1 273/4885ALDH1A1 265/4885POLB 2421/4885 |
| US-10358422-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | LSS, COASY, ADH1A | MEN1 273/4885ALDH1A1 265/4885POLB 2421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.