Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295024 | 0.82 | ACHE (0.45) | ABCB1ABCG2TSHRRECQLSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4364214 | 0.75 | TACR1 (0.40) | — | |
| SCHEMBL9220425 | 0.73 | L3MBTL1 (0.45) | ABCB1ABCG2TSHRRECQLSMN1; SMN2 | |
| SCHEMBL3842028 | 0.71 | PSEN1 (0.46) | ABCB1ABCG2BLMTSHRRECQL | |
| SCHEMBL5544976 | 0.70 | ACHE (0.45) | ABCB1ABCG2TSHRRECQLSMN1; SMN2 | |
| SCHEMBL13385223 | 0.68 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL2887859 | 0.68 | CNR2 (0.53) | TSHRCNR2CNR1 | |
| SCHEMBL2887853 | 0.68 | CNR2 (0.53) | TSHRCNR2CNR1 | |
| SCHEMBL8253035 | 0.67 | NPC1 (0.54) | ACHEL3MBTL1 | |
| SCHEMBL8243019 | 0.67 | NPC1 (0.54) | ACHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360293-B1 | Process for the preparation of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines | LONZA AG (CH) | 1995-08-30 | — | — | EP | disclosed |
| US-4990618-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-c]-pyridines | LONZA LTD. (CH) | 1991-02-05 | — | — | US | disclosed |
| US-4965359-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-C]-pyridines | LONZA LTD. (CH) | 1990-10-23 | — | — | US | disclosed |