Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 8/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197844 | 1.00 | HTR1A (0.39) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL9197856 | 1.00 | HTR1A (0.39) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL9530286 | 0.82 | KCNE1 (0.53) | KCNE1KCNQ1KDM4EL3MBTL1ABCB1 | |
| SCHEMBL8946767 | 0.82 | KCNE1 (0.37) | KCNE1KCNQ1KDM4EL3MBTL1ABCB1 | |
| SCHEMBL9198446 | 0.82 | KCNE1 (0.37) | KCNE1KCNQ1KDM4EL3MBTL1ABCB1 | |
| SCHEMBL8946770 | 0.82 | KCNE1 (0.37) | KCNE1KCNQ1KDM4EL3MBTL1ABCB1 | |
| SCHEMBL9530280 | 0.82 | KCNE1 (0.53) | KCNE1KCNQ1KDM4EL3MBTL1ABCB1 | |
| SCHEMBL9032549 | 0.82 | KCNE1 (0.56) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL9032544 | 0.82 | KCNE1 (0.56) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL9198451 | 0.82 | KCNE1 (0.37) | KCNE1KCNQ1KDM4EL3MBTL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389861-B1 | Benzopyran derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-08-23 | — | — | EP | disclosed |
| US-5210234-A | Benzopyran intermediates | BEECHAM GROUP P.L.C. (GB) | 1993-05-11 | — | — | US | disclosed |
| US-5104890-A | Potassium channel activtors; vasodilators | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0250077-B1 | PHARMACOLOGICALLY ACTIVE BENZOPYRANES | BEECHAM GROUP PLC (GB) | 1992-01-02 | — | — | EP | disclosed |
| US-5075460-A | Hypotensive agents | BEECHAM GROUP PLC (GB) | 1991-12-24 | — | — | US | disclosed |
| EP-0389861-A1 | Benzopyran derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-03 | — | — | EP | disclosed |
| US-4943582-A | Active compounds | BEECHAM GROUP P.L.C. (GB) | 1990-07-24 | — | — | US | disclosed |
| EP-0250077-A2 | Pharmacologically active benzopyranes | BEECHAM GROUP PLC (GB) | 1987-12-23 | — | — | EP | disclosed |