Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 3/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942481 | 0.80 | NR5A1 (0.50) | MEN1KMT2ALMNAALDH1A1L3MBTL1 | |
| SCHEMBL16352314 | 0.75 | LMNA (0.56) | ESR1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8766728 | 0.75 | LMNA (0.56) | ESR1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6579897 | 0.74 | ESR1 (0.56) | ESR1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11095674 | 0.74 | NR5A1 (0.79) | LMNANR5A1RAB9ALTA4HTP53 | |
| SCHEMBL2829024 | 0.74 | NR5A1 (0.79) | LMNANR5A1RAB9ALTA4HTP53 | |
| SCHEMBL28373061 | 0.74 | NR5A1 (0.79) | LMNANR5A1RAB9ALTA4HTP53 | |
| SCHEMBL1573968 | 0.74 | NR5A1 (0.79) | LMNANR5A1RAB9ALTA4HTP53 | |
| SCHEMBL5473083 | 0.74 | NR5A1 (0.79) | LMNANR5A1RAB9ALTA4HTP53 | |
| SCHEMBL8936597 | 0.74 | NR5A1 (0.79) | LMNANR5A1RAB9ALTA4HTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8614348-B2 | Diamantane compounds, liquid crystalline compounds, and liquid crystalline compositions | National University Corporation Yokohama National University (JP) | 2013-12-24 | — | — | US | disclosed |
| US-20110015426-A1 | NOVEL DIAMANTANE COMPOUNDS, LIQUID CRYSTALLINE COMPOUNDS, AND LIQUID CRYSTALLINE COMPOSITIONS | NATIONAL UNIVERSITY CORPORATION YOKOHAMA (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20110015426-A1 | NOVEL DIAMANTANE COMPOUNDS, LIQUID CRYSTALLINE COMPOUNDS, AND LIQUID CRYSTALLINE COMPOSITIONS | NATIONAL UNIVERSITY CORPORATION YOKOHAMA (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20110015426-A1 | NOVEL DIAMANTANE COMPOUNDS, LIQUID CRYSTALLINE COMPOUNDS, AND LIQUID CRYSTALLINE COMPOSITIONS | NATIONAL UNIVERSITY CORPORATION YOKOHAMA (JP) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015426-A1 | NOVEL DIAMANTANE COMPOUNDS, LIQUID CRYSTALLINE COMPOUNDS, AND LIQUID CRYSTALLINE COMPOSITIONS | CDK2, CCNT1, CCND1 | ESR1 4743/4885MEN1 3450/4885KMT2A 1859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.