SCHEMBL8766728

SCHEMBL8766728

COc1ccc(C23CC4CC(C2)CC(c2ccc(OC)cc2)(C4)C3)cc1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HSD11B1 P28845 2/20 0.54
ESR1 P03372 1/20 0.52
MAOB P27338 2/20 0.49
MAOA P21397 1/20 0.49
PGR P06401 3/20 0.47
ALDH1A1 P00352 4/20 0.47
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16352314 1.00 LMNA (0.56) LMNASMN1; SMN2HSD11B1ESR1MAOB
SCHEMBL12276579 0.93 SMN1; SMN2 (0.65) LMNASMN1; SMN2HSD11B1ESR1KMT2A
SCHEMBL8767208 0.90 LMNA (0.52) LMNASMN1; SMN2HSD11B1ESR1MAOB
SCHEMBL12040557 0.89 LMNA (0.57) LMNASMN1; SMN2HSD11B1MAOBMAOA
SCHEMBL822923 0.88 LMNA (0.57) LMNASMN1; SMN2HSD11B1ESR1PGR
SCHEMBL31525726 0.84 MAOB (0.55) LMNASMN1; SMN2HSD11B1MAOBMAOA
SCHEMBL12936217 0.83 KMT2A (0.66) LMNASMN1; SMN2HSD11B1ALDH1A1KMT2A
SCHEMBL18043699 0.82 CA1 (0.55) MAOBMAOAALDH1A1GRIN1GRIN2A
SCHEMBL17855983 0.81 HSD11B1 (0.44) LMNASMN1; SMN2HSD11B1ESR1MAOB
SCHEMBL11545749 0.79 MEN1 (0.62) LMNASMN1; SMN2HSD11B1PGRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235115-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-07-27 US disclosed
US-8916672-B2 Transparent polyarylene ether polymer with high heat resistance and method for preparing the same ICUF-HYU (Industry-University Cooperation Foundation Hanyang University) (KR) 2014-12-23 US disclosed
US-20120130041-A1 Transparent Polyarylene Ether Polymer With High Heat Resistance And Method For Preparing The Same IUCF-HYU (Industry-University Coperation Foundatio Hanyang University (KR) 2012-05-24 US disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed