Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204340 | 0.89 | FFAR1 (0.37) | IDO1FFAR1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9205215 | 0.81 | IDO1 (0.42) | IDO1CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL9197120 | 0.73 | ALOX5 (0.38) | IDO1CDK5CDK5R1FFAR1ALDH1A1 | |
| SCHEMBL9200198 | 0.73 | ALOX5 (0.38) | IDO1CDK5CDK5R1FFAR1ALDH1A1 | |
| SCHEMBL9195547 | 0.71 | IDO1 (0.43) | IDO1CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL9852592 | 0.69 | IDO1 (0.43) | IDO1EPHX1HPGDSMN1; SMN2MAPT | |
| SCHEMBL8604028 | 0.68 | IDO1 (0.43) | IDO1CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL8439880 | 0.68 | IDO1 (0.43) | IDO1CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL9206135 | 0.67 | IDO1 (0.43) | IDO1CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL9201296 | 0.67 | CRBN (0.41) | IDO1ALDH1A1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406863-B1 | Cyclic amidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1995-05-24 | — | — | EP | disclosed |
| US-5100888-A | Bactericides | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-31 | — | — | US | disclosed |
| EP-0406863-A1 | Cyclic amidinylthiocarbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-01-09 | — | — | EP | disclosed |