Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192878 | 0.94 | LTB4R (0.88) | LTB4RLTB4R2 | |
| SCHEMBL8990430 | 0.93 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL31539110 | 0.89 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL1891598 | 0.89 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9194548 | 0.88 | LTB4R (0.87) | LTB4RLTB4R2 | |
| SCHEMBL8990429 | 0.87 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9196119 | 0.87 | LTB4R (0.80) | LTB4RLTB4R2 | |
| SCHEMBL9198403 | 0.87 | LTB4R (0.87) | LTB4RLTB4R2 | |
| SCHEMBL9373296 | 0.87 | LTB4R (0.67) | LTB4RLTB4R2 | |
| SCHEMBL9198578 | 0.86 | LTB4R (0.88) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527922-B1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | SEARLE & CO (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5212198-A | Antiinflammatory agents | G. D. SEARLE & CO. (US) | 1993-05-18 | — | — | US | disclosed |
| US-5192782-A | Leukotriene antagonists, antiinflammatory agents | G. D. SEARLE & CO. (US) | 1993-03-09 | — | — | US | disclosed |
| US-5073562-A | Antiinflammatory agents; leukotriene by antagonists | G. D. SEARLE & CO. (US) | 1991-12-17 | — | — | US | disclosed |