Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31539110 | 1.00 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL8990430 | 0.95 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL8990429 | 0.91 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9198076 | 0.90 | LTB4R (0.81) | LTB4RLTB4R2 | |
| SCHEMBL9198565 | 0.89 | LTB4R (0.87) | LTB4RLTB4R2 | |
| SCHEMBL9378602 | 0.87 | LTB4R (0.77) | LTB4RLTB4R2 | |
| SCHEMBL9376755 | 0.87 | LTB4R (0.77) | LTB4RLTB4R2 | |
| SCHEMBL9196119 | 0.85 | LTB4R (0.80) | LTB4RLTB4R2 | |
| SCHEMBL9192878 | 0.85 | LTB4R (0.88) | LTB4RLTB4R2 | |
| SCHEMBL8990416 | 0.84 | LTB4R (0.78) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190216790-A1 | Methods for Treating Pruritis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-07-18 | — | — | US | claimed |
| WO-2018071687-A1 | METHODS OF TREATING PRURITIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-19 | — | — | WO | claimed |
| US-20170333516-A1 | PREVENTIVE OR THERAPEUTIC AGENT FOR AGE-RELATED MACULAR DEGENERATION | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2017-11-23 | — | — | US | claimed |
| WO-2001034199-A2 | ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER | ELI LILLY AND COMPANY (US) | 2001-05-17 | — | — | WO | claimed |
| EP-0527922-B1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | SEARLE & CO (US) | 1995-03-08 | — | — | EP | claimed |
| EP-0527922-A1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF. | SEARLE & CO (US) | 1993-02-24 | — | — | EP | claimed |
| US-5073562-A | Antiinflammatory agents; leukotriene by antagonists | G. D. SEARLE & CO. (US) | 1991-12-17 | — | — | US | claimed |
| WO-1991017160-A1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | G.D. SEARLE & CO. (US) | 1991-11-14 | — | — | WO | claimed |
| US-10849954-B2 | Preventive or therapeutic agent for age-related macular degeneration | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2020-12-01 | — | — | US | disclosed |
| US-20190216790-A1 | Methods for Treating Pruritis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-07-18 | — | — | US | disclosed |
| US-20170333516-A1 | PREVENTIVE OR THERAPEUTIC AGENT FOR AGE-RELATED MACULAR DEGENERATION | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2017-11-23 | — | — | US | disclosed |
| EP-2471954-B1 | Genetic susceptibility variants associated with cardiovascular disease | DECODE GENETICS EHF (IS) | 2016-08-24 | — | — | EP | disclosed |
| US-20160166508-A1 | Method and Composition for Treating Inflammatory Disorders | MEDA AB (SE) | 2016-06-16 | — | — | US | disclosed |
| US-20160166508-A1 | Method and Composition for Treating Inflammatory Disorders | MEDA AB (SE) | 2016-06-16 | — | — | US | disclosed |
| WO-1995032201-A1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-SULFONIMIDES DERIVATIVES, THEIR PREPARATION AND THEIR USE AS LEUKOTRIENE B4 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-11-30 | — | — | WO | disclosed |
| EP-0527922-B1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | SEARLE & CO (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5212198-A | Antiinflammatory agents | G. D. SEARLE & CO. (US) | 1993-05-18 | — | — | US | disclosed |
| US-5192782-A | Leukotriene antagonists, antiinflammatory agents | G. D. SEARLE & CO. (US) | 1993-03-09 | — | — | US | disclosed |
| EP-0527922-A1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF. | SEARLE & CO (US) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991017160-A1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | G.D. SEARLE & CO. (US) | 1991-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10849954-B2 | Preventive or therapeutic agent for age-related macular degeneration | LTB4R, LTA4H, LTB4R2 | LTB4R 1/4885LTB4R2 3/4885 |
| US-20190216790-A1 | Methods for Treating Pruritis | ITCH, CYSLTR2, CYSLTR1 | LTB4R 8/4885LTB4R2 4/4885 |
| US-20170333516-A1 | PREVENTIVE OR THERAPEUTIC AGENT FOR AGE-RELATED MACULAR DEGENERATION | LTB4R, LTA4H, LTB4R2 | LTB4R 1/4885LTB4R2 3/4885 |
| US-20160166508-A1 | Method and Composition for Treating Inflammatory Disorders | LIPA, HRH2, HRH1 | LTB4R 8/4885LTB4R2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.