Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198654 | 1.00 | MEN1 (0.44) | MEN1KMT2AACE2GPR84FFAR1 | |
| SCHEMBL9194621 | 0.98 | MEN1 (0.41) | MEN1KMT2AACE2GPR84FFAR1 | |
| SCHEMBL9194614 | 0.98 | MEN1 (0.41) | MEN1KMT2AACE2GPR84FFAR1 | |
| SCHEMBL9201009 | 0.92 | DDAH1 (0.40) | MEN1KMT2AACE2GPR84FFAR1 | |
| SCHEMBL9201005 | 0.92 | DDAH1 (0.40) | MEN1KMT2AACE2GPR84FFAR1 | |
| SCHEMBL29049840 | 0.82 | ACE2 (0.56) | MEN1KMT2AACE2GPR84FFAR1 | |
| SCHEMBL9193607 | 0.81 | MEN1 (0.44) | MEN1KMT2AACE2GPR84FFAR1 | |
| SCHEMBL9193598 | 0.81 | MEN1 (0.44) | MEN1KMT2AACE2GPR84FFAR1 | |
| SCHEMBL9198633 | 0.80 | GPR84 (0.44) | MEN1KMT2AACE2GPR84FFAR1 | |
| SCHEMBL9196419 | 0.80 | GPR84 (0.44) | MEN1KMT2AACE2GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503634-B1 | Novel terpene derivatives and process for preparing the same | EISAI CO LTD (JP) | 1995-12-27 | — | — | EP | claimed |