Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844511 | 1.00 | TDP1 (0.45) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9199071 | 0.91 | TDP1 (0.47) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9204726 | 0.90 | ALDH1A1 (0.43) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL28803113 | 0.90 | POLB (0.48) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8579324 | 0.90 | POLB (0.48) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8579326 | 0.90 | POLB (0.48) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL5391199 | 0.90 | POLB (0.48) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL28459037 | 0.90 | POLB (0.48) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9207674 | 0.90 | POLB (0.48) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL5391201 | 0.90 | POLB (0.48) | TDP1ATMALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411636-B1 | Piperidylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5153188-A | Thienamycin antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |