Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | GPR4 | P46093 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199170 | 0.88 | AGTR2 (0.49) | AGTR2AGTR1 | |
| SCHEMBL9205496 | 0.87 | AGTR1 (0.51) | AGTR2AGTR1GPR4 | |
| SCHEMBL9200041 | 0.85 | AGTR1 (0.55) | AGTR2AGTR1GPR4 | |
| SCHEMBL9200060 | 0.84 | AGTR2 (0.54) | AGTR2AGTR1 | |
| SCHEMBL9202793 | 0.83 | AGTR2 (0.51) | AGTR2AGTR1GPR4 | |
| SCHEMBL9205503 | 0.83 | AGTR2 (0.49) | AGTR2AGTR1 | |
| SCHEMBL9202804 | 0.81 | AGTR2 (0.51) | AGTR2AGTR1 | |
| SCHEMBL21083598 | 0.81 | AGTR2 (0.55) | AGTR2AGTR1 | |
| SCHEMBL9204771 | 0.81 | AGTR1 (0.49) | AGTR2AGTR1GPR4 | |
| SCHEMBL9204789 | 0.79 | AGTR2 (0.48) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517812-A4 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO INC (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0517812-A1 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-16 | — | — | EP | disclosed |