Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299426 | 0.88 | CYP1A2 (0.57) | ALDH1A1KMT2ARAB9APKMCYP1A2 | |
| SCHEMBL11139407 | 0.86 | CA12 (0.58) | ALDH1A1KMT2ARAB9APKMCYP1A2 | |
| SCHEMBL1259319 | 0.82 | CYP1A2 (0.57) | ALDH1A1KMT2ACYP1A2CYP2C19MEN1 | |
| SCHEMBL4003419 | 0.81 | ALDH1A1 (0.69) | ALDH1A1KMT2ARAB9APKMCYP1A2 | |
| SCHEMBL848822 | 0.81 | ALDH1A1 (0.69) | ALDH1A1KMT2ARAB9APKMCYP1A2 | |
| SCHEMBL11129650 | 0.81 | KMT2A (0.70) | ALDH1A1KMT2ARAB9APKMCYP1A2 | |
| SCHEMBL13384768 | 0.80 | CYP1A2 (0.58) | ALDH1A1KMT2ACYP1A2CYP2C19MEN1 | |
| SCHEMBL11184694 | 0.80 | CYP1A2 (0.58) | ALDH1A1KMT2ACYP1A2CYP2C19MEN1 | |
| SCHEMBL7925078 | 0.80 | ALDH1A1 (0.68) | ALDH1A1KMT2ARAB9APKMCYP1A2 | |
| SCHEMBL19448886 | 0.80 | PKM (0.68) | ALDH1A1KMT2ARAB9APKMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1030075-C | 3-cycloalkyl-propionamides, their tautomers and their salts, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1995-10-18 | — | — | CN | disclosed |
| EP-0484223-B1 | 3-Cycloalkylpropanamides, their tautomers and salts, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL UCLAF (FR) | 1995-03-08 | — | — | EP | disclosed |
| US-5384423-A | Intermediates for antiinflammatory agents | ROUSSEL-UCLAF (FR) | 1995-01-24 | — | — | US | disclosed |
| US-5308865-A | Antiinflammatory agents | ROUSSEL UCLAF (FR) | 1994-05-03 | — | — | US | disclosed |
| US-5240960-A | Antiinflammatory agents | ROUSSEL UCLAF (FR) | 1993-08-31 | — | — | US | disclosed |
| CN-1064482-A | New 3-cycloalkyl-propanamides, the preparation method of their tautomer and its esters | ROUSSEL UCLAF (FR) | 1992-09-16 | — | — | CN | disclosed |
| EP-0484223-A2 | 3-Cycloalkylpropanamides, their tautomers and salts, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1992-05-06 | — | — | EP | disclosed |
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |