Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651999 | 0.94 | CNR1 (0.43) | CNR1CNR2NPY1RNPY2RNPY5R | |
| Hydrochloric Acid SCHEMBL8120200 | 0.93 | CNR1 (0.43) | CNR1CNR2NPY1RNPY2RNPY5R | |
| SCHEMBL9200838 | 0.92 | CNR1 (0.42) | CNR1CNR2NPY1RTDP1 | |
| SCHEMBL9195693 | 0.91 | NPY1R (0.42) | CNR1CNR2NPY1RNPY2RNPY5R | |
| SCHEMBL9201122 | 0.90 | TDP1 (0.48) | CNR1TMEM97SIGMAR1LMNATDP1 | |
| SCHEMBL9196217 | 0.90 | MEN1 (0.42) | CNR1CNR2NPSR1TDP1CASR | |
| SCHEMBL9275609 | 0.88 | CYP2C9 (0.38) | CNR1CNR2LMNAMAPTTDP1 | |
| SCHEMBL9195083 | 0.87 | CNR1 (0.43) | CNR1CNR2SIGMAR1NPSR1TDP1 | |
| SCHEMBL9194746 | 0.87 | CNR1 (0.43) | CNR1CNR2SIGMAR1NPSR1TDP1 | |
| SCHEMBL30905434 | 0.86 | CNR1 (0.41) | CNR1CNR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |