Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 6/20 | 0.43 |
| ▸ | JAK2 | O60674 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949580 | 0.82 | SIRT2 (0.50) | MEN1KMT2AJAK3JAK2GABRB2 | |
| SCHEMBL9205883 | 0.80 | GUSB (0.45) | — | |
| SCHEMBL4376723 | 0.80 | KDM4E (0.49) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9199571 | 0.76 | KDM4E (0.67) | CSNK1DCA12CA1CA2CA7 | |
| SCHEMBL15215750 | 0.74 | KMT2A (0.52) | MEN1KMT2AGABRA1GABRB2ALDH1A1 | |
| SCHEMBL2845477 | 0.72 | MEN1 (0.50) | MEN1KMT2AJAK3JAK2GABRA1 | |
| SCHEMBL15015768 | 0.70 | MEN1 (0.51) | MEN1KMT2AGABRA1GABRB2ALDH1A1 | |
| SCHEMBL4415499 | 0.69 | MEN1 (0.50) | MEN1KMT2AJAK3JAK2GABRA1 | |
| SCHEMBL3228479 | 0.68 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15333212 | 0.68 | KMT2A (0.53) | MEN1KMT2AGABRA1GABRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341948-B1 | Cephalosporins, process for their preparation and pharmaceutical compositions | ICI PLC (GB) | 1995-01-11 | — | — | EP | disclosed |
| US-5149803-A | Intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-09-22 | — | — | US | disclosed |
| US-5055462-A | CEPHALOSPORIN COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0341948-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions | ZENECA LIMITED (GB) | 1989-11-15 | — | — | EP | disclosed |