Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208996 | 1.00 | RAB9A (0.46) | RAB9ANPC1TDP1IDO1ALDH1A1 | |
| SCHEMBL9728072 | 1.00 | RAB9A (0.46) | RAB9ANPC1TDP1IDO1ALDH1A1 | |
| SCHEMBL9196975 | 0.91 | RAB9A (0.45) | RAB9ANPC1TDP1IDO1ALDH1A1 | |
| SCHEMBL9020617 | 0.91 | RAB9A (0.43) | RAB9ANPC1TDP1IDO1ALDH1A1 | |
| SCHEMBL8541140 | 0.90 | RAB9A (0.41) | RAB9ANPC1TDP1ALDH1A1ATM | |
| SCHEMBL8438677 | 0.90 | RAB9A (0.41) | RAB9ANPC1TDP1ALDH1A1ATM | |
| SCHEMBL5719627 | 0.90 | TDP1 (0.46) | RAB9ANPC1TDP1IDO1ALDH1A1 | |
| SCHEMBL9728572 | 0.90 | TDP1 (0.48) | RAB9ANPC1TDP1IDO1ALDH1A1 | |
| SCHEMBL9204434 | 0.90 | TDP1 (0.48) | RAB9ANPC1TDP1IDO1ALDH1A1 | |
| SCHEMBL9204969 | 0.90 | TDP1 (0.46) | RAB9ANPC1TDP1IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126587-B1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMA (JP) | 1995-04-19 | — | — | EP | disclosed |