Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541140 | 1.00 | RAB9A (0.41) | RAB9ANPC1ALDH1A1LMNADPP8 | |
| SCHEMBL8434820 | 0.91 | TDP1 (0.43) | ALDH1A1LMNADPP8DPP9TDP1 | |
| SCHEMBL9208996 | 0.90 | RAB9A (0.46) | RAB9ANPC1ALDH1A1LMNADPP8 | |
| SCHEMBL9199587 | 0.90 | RAB9A (0.46) | RAB9ANPC1ALDH1A1LMNADPP8 | |
| SCHEMBL9728072 | 0.90 | RAB9A (0.46) | RAB9ANPC1ALDH1A1LMNADPP8 | |
| SCHEMBL8435953 | 0.90 | PDK1 (0.45) | ALDH1A1LMNADPP8DPP9TDP1 | |
| SCHEMBL8435956 | 0.90 | PDK1 (0.45) | ALDH1A1LMNADPP8DPP9TDP1 | |
| SCHEMBL8588093 | 0.90 | PDK1 (0.45) | ALDH1A1LMNADPP8DPP9TDP1 | |
| SCHEMBL9728223 | 0.88 | DPP8 (0.46) | DPP8DPP9TDP1 | |
| SCHEMBL9040433 | 0.87 | ALDH1A1 (0.41) | ALDH1A1LMNATDP1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |