Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11156557 | 0.80 | KDM4E (0.51) | ALDH1A1LMNAL3MBTL1SMN1; SMN2CYP2C9 | |
| SCHEMBL9199776 | 0.80 | LMNA (0.39) | ALDH1A1LMNAL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL20027633 | 0.76 | HPGD (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9ACYP2C9 | |
| SCHEMBL9593142 | 0.75 | KDM4E (0.46) | ALDH1A1LMNAL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL3355557 | 0.69 | KDM4E (0.42) | ALDH1A1LMNASMN1; SMN2CYP2C9KDM4E | |
| SCHEMBL30852420 | 0.66 | KDM4E (0.46) | ALDH1A1LMNAPOLBCYP2C9KDM4E | |
| SCHEMBL12376645 | 0.66 | RIPK1 (0.43) | ALDH1A1LMNASMN1; SMN2RAB9ARIPK1 | |
| SCHEMBL12376693 | 0.66 | ADORA2A (0.59) | ALDH1A1LMNANPC1KDM4EGAA | |
| SCHEMBL6416083 | 0.65 | NPC1 (0.60) | LMNASMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL7721933 | 0.65 | SMN1; SMN2 (0.42) | ALDH1A1LMNAL3MBTL1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418667-B1 | Carboxylic acid amides | BASF AG (DE) | 1995-08-16 | — | — | EP | disclosed |
| US-5201932-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |