Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203639 | 0.93 | AGTR2 (0.32) | AGTR2AGTR1MAPT | |
| SCHEMBL9203347 | 0.89 | MAPT (0.35) | AGTR2AGTR1MAPTMEN1KMT2A | |
| SCHEMBL9200703 | 0.85 | PDE10A (0.38) | AGTR2AGTR1MAPT | |
| SCHEMBL9203335 | 0.85 | MAPT (0.36) | AGTR2AGTR1MAPT | |
| SCHEMBL9286231 | 0.84 | AGTR2 (0.31) | AGTR2AGTR1 | |
| SCHEMBL9200951 | 0.84 | MAPT (0.33) | AGTR2AGTR1MAPT | |
| SCHEMBL9205503 | 0.83 | AGTR2 (0.49) | AGTR2AGTR1 | |
| SCHEMBL9203634 | 0.83 | MAPT (0.34) | AGTR2AGTR1MAPT | |
| SCHEMBL9203059 | 0.81 | AGTR1 (0.36) | AGTR2AGTR1 | |
| SCHEMBL9205216 | 0.79 | AGTR2 (0.38) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517812-A4 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO INC (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0517812-A1 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-16 | — | — | EP | disclosed |