Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 12/20 | 0.78 |
| ▸ | ADRA1D | P25100 | 11/20 | 0.78 |
| ▸ | ADRA1B | P35368 | 11/20 | 0.78 |
| ▸ | HTR1A | P08908 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193925 | 0.95 | ADRA1D (0.87) | ADRA1AADRA1DADRA1BHTR1ALMNA | |
| SCHEMBL9200004 | 0.93 | ADRA1A (0.90) | ADRA1AADRA1DADRA1BHTR1ALMNA | |
| SCHEMBL9468949 | 0.93 | ADRA1A (0.78) | ADRA1AADRA1DADRA1BHTR1ALMNA | |
| SCHEMBL9201176 | 0.90 | ADRA1A (0.66) | ADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL9486450 | 0.90 | ADRA1A (0.73) | ADRA1AADRA1DADRA1BHTR1ALMNA | |
| SCHEMBL9317007 | 0.88 | ADRA1D (0.87) | ADRA1AADRA1DADRA1BHTR1ALMNA | |
| SCHEMBL5597266 | 0.88 | ADRA1D (1.00) | ADRA1AADRA1DADRA1BHTR1ALMNA | |
| SCHEMBL9195086 | 0.86 | ADRA1D (0.63) | ADRA1AADRA1DADRA1BHTR1ALMNA | |
| SCHEMBL9197027 | 0.86 | ADRA1A (0.70) | ADRA1AADRA1DADRA1BHTR1ALMNA | |
| SCHEMBL9202997 | 0.86 | ADRA1A (0.65) | ADRA1AADRA1DADRA1BHTR1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520883-B1 | 2-Aminopyrimidin-4-carboxamide derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1995-07-12 | — | — | EP | disclosed |
| EP-0520883-A1 | 2-Aminopyrimidin-4-carboxamide derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1992-12-30 | — | — | EP | disclosed |