Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 9/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | PGR | P06401 | 2/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | SHBG | P04278 | 1/20 | 0.66 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200297 | 1.00 | HIF1A (0.66) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL9205611 | 0.99 | HIF1A (0.65) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL9205622 | 0.99 | HIF1A (0.65) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| SCHEMBL9200171 | 0.92 | HIF1A (0.65) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| SCHEMBL9200163 | 0.92 | HIF1A (0.65) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL9201448 | 0.91 | HIF1A (0.64) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL9206099 | 0.91 | HIF1A (0.64) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| SCHEMBL12397331 | 0.87 | HIF1A (0.74) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| SCHEMBL12397343 | 0.86 | HIF1A (0.72) | HIF1ANR3C1SMN1; SMN2CYP2C19HSD17B10 | |
| SCHEMBL9198293 | 0.86 | NR3C1 (0.66) | HIF1ANR3C1CYP2C19HSD17B10PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238545-B1 | C20 THROUGH C26 AMINO STEROIDS | UPJOHN CO (US) | 1995-11-15 | — | — | EP | claimed |
| EP-0263213-B1 | C20 Through C26 amino steroids | UPJOHN CO (US) | 1995-09-06 | — | — | EP | claimed |
| US-5380839-A | Antitumor agents, antisecretory agents, enzyme inhibitors or antiasthmatics | THE UPJOHN COMPANY (US) | 1995-01-10 | — | — | US | claimed |
| EP-0263213-A1 | C20 Through C26 amino steroids | THE UPJOHN COMPANY (US) | 1988-04-13 | — | — | EP | claimed |