Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106975 | 0.85 | KMT2A (0.62) | KMT2AALDH1A1TP53LMNAGAA | |
| SCHEMBL8338185 | 0.83 | KMT2A (0.56) | KMT2AALDH1A1TP53LMNAGAA | |
| SCHEMBL18906021 | 0.81 | KMT2A (0.61) | KMT2AALDH1A1TP53LMNAGAA | |
| SCHEMBL15743809 | 0.81 | KMT2A (0.57) | KMT2AALDH1A1TP53LMNAGAA | |
| SCHEMBL21041221 | 0.79 | KMT2A (0.68) | KMT2AALDH1A1TP53LMNAGAA | |
| SCHEMBL24882693 | 0.78 | KMT2A (0.55) | KMT2AALDH1A1TP53LMNAGAA | |
| SCHEMBL27281106 | 0.78 | ALDH1A1 (0.62) | KMT2AALDH1A1TP53LMNAGAA | |
| SCHEMBL18546466 | 0.78 | ALDH1A1 (0.62) | KMT2AALDH1A1TP53LMNAGAA | |
| SCHEMBL23801582 | 0.77 | KMT2A (0.57) | KMT2AALDH1A1TP53LMNAGAA | |
| SCHEMBL14664119 | 0.77 | KMT2A (0.54) | KMT2AALDH1A1TP53LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520883-B1 | 2-Aminopyrimidin-4-carboxamide derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1995-07-12 | — | — | EP | disclosed |
| US-5244894-A | Treating disorders involving hyperactivity of the alpha 1-adrenergic system in lower urinary tract | SYNTHELABO | 1993-09-14 | — | — | US | disclosed |
| EP-0520883-A1 | 2-Aminopyrimidin-4-carboxamide derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1992-12-30 | — | — | EP | disclosed |