Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPOR | P19235 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200553 | 1.00 | MTNR1A (0.41) | MTNR1AMTNR1BSIGMAR1TDP1EPOR | |
| SCHEMBL9199630 | 0.91 | MTNR1A (0.44) | MTNR1AMTNR1BSIGMAR1TDP1 | |
| SCHEMBL9199621 | 0.91 | MTNR1A (0.44) | MTNR1AMTNR1BSIGMAR1TDP1 | |
| SCHEMBL9194746 | 0.90 | CNR1 (0.43) | SIGMAR1TDP1NR1H3CASRALDH1A1 | |
| SCHEMBL9195083 | 0.90 | CNR1 (0.43) | SIGMAR1TDP1NR1H3CASRALDH1A1 | |
| SCHEMBL9271707 | 0.87 | MEN1 (0.38) | — | |
| SCHEMBL9199350 | 0.87 | MEN1 (0.38) | — | |
| SCHEMBL8058775 | 0.86 | MTNR1A (0.44) | MTNR1AMTNR1BSIGMAR1TDP1 | |
| SCHEMBL8526750 | 0.85 | NPY1R (0.38) | — | |
| SCHEMBL6901612 | 0.84 | CNR1 (0.43) | SIGMAR1TDP1NR1H3CASRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |