Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199621 | 0.95 | MTNR1A (0.44) | MTNR1AMTNR1BSIGMAR1KMT2ATDP1 | |
| SCHEMBL9199630 | 0.95 | MTNR1A (0.44) | MTNR1AMTNR1BSIGMAR1KMT2ATDP1 | |
| SCHEMBL8058871 | 0.90 | ALDH1A1 (0.42) | KMT2ATDP1 | |
| SCHEMBL8068125 | 0.89 | FOLH1 (0.42) | MTNR1AMTNR1BSIGMAR1KMT2A | |
| SCHEMBL1388287 | 0.88 | CNR1 (0.45) | — | |
| SCHEMBL8068235 | 0.86 | MTNR1A (0.40) | MTNR1AMTNR1BKMT2ATDP1 | |
| SCHEMBL9200553 | 0.86 | MTNR1A (0.41) | MTNR1AMTNR1BSIGMAR1TDP1 | |
| SCHEMBL9200548 | 0.86 | MTNR1A (0.41) | MTNR1AMTNR1BSIGMAR1TDP1 | |
| SCHEMBL8069613 | 0.86 | PLAAT3 (0.38) | — | |
| SCHEMBL9194825 | 0.85 | ALDH1A1 (0.42) | KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |