Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYLK | Q15746 | 4/20 | 0.68 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 8/20 | 0.58 |
| ▸ | PRKCG | P05129 | 8/20 | 0.58 |
| ▸ | PRKCB | P05771 | 8/20 | 0.58 |
| ▸ | PRKCA | P17252 | 8/20 | 0.58 |
| ▸ | PRKCH | P24723 | 8/20 | 0.58 |
| ▸ | PRKCI | P41743 | 8/20 | 0.58 |
| ▸ | PRKCE | Q02156 | 8/20 | 0.58 |
| ▸ | PRKCQ | Q04759 | 8/20 | 0.58 |
| ▸ | PRKCZ | Q05513 | 8/20 | 0.58 |
| ▸ | PRKCD | Q05655 | 8/20 | 0.58 |
| ▸ | PRKD1 | Q15139 | 8/20 | 0.58 |
| ▸ | GLI1 | P08151 | 1/20 | 0.50 |
| ▸ | GLI2 | P10070 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | PRKACG | P22612 | 1/20 | 0.50 |
| ▸ | PRKACB | P22694 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204105 | 0.97 | MYLK (0.63) | MYLKROCK2PRKD3PRKCGPRKCB | |
| SCHEMBL9200049 | 0.92 | MYLK (0.61) | MYLKROCK2PRKD3PRKCGPRKCB | |
| SCHEMBL9202582 | 0.90 | MYLK (0.60) | MYLKROCK2PRKD3PRKCGPRKCB | |
| SCHEMBL9201754 | 0.88 | MYLK (0.57) | MYLKROCK2PRKD3PRKCGPRKCB | |
| SCHEMBL9197980 | 0.88 | MYLK (0.61) | MYLKROCK2PRKD3PRKCGPRKCB | |
| SCHEMBL9200653 | 0.87 | MYLK (0.56) | MYLKROCK2PRKD3PRKCGPRKCB | |
| SCHEMBL9198042 | 0.84 | MYLK (0.56) | MYLKROCK2PRKD3PRKCGPRKCB | |
| SCHEMBL9544843 | 0.82 | ROCK2 (0.67) | MYLKROCK2PRKD3PRKCGPRKCB | |
| SCHEMBL9195167 | 0.81 | ROCK2 (0.74) | MYLKROCK2PRKD3PRKCGPRKCB | |
| SCHEMBL9200997 | 0.81 | MYLK (1.00) | MYLKROCK2PRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993024490-A1 | USE OF INDOLOCARBAZOLS IN AIDS TREATMENT | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | claimed |
| US-5476944-A | Inhibitors or stimulators of superoxide generation; may also inhibit cyclooxygenase and/or 5-lipoxygenase; useful in therapeutic or prophylactic treatment of disease conditions | G. D. SEARLE & CO. (US) | 1995-12-19 | — | — | US | disclosed |
| US-5438050-A | Indolocarbazole derivatives, processes for their preparation and compositions containing them | GODECKE AKTIENGESELLSCHAFT (DE) | 1995-08-01 | — | — | US | disclosed |
| EP-0328000-B1 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GOEDECKE AG (DE) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993024490-A1 | USE OF INDOLOCARBAZOLS IN AIDS TREATMENT | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | disclosed |
| EP-0328000-A2 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1989-08-16 | — | — | EP | disclosed |