Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 8/20 | 0.80 |
| ▸ | AGTR2 | P50052 | 8/20 | 0.80 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196982 | 0.89 | AGTR1 (0.80) | AGTR1AGTR2DRD2TBXA2RPPARG | |
| SCHEMBL9198204 | 0.89 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9275378 | 0.86 | AGTR1 (0.78) | AGTR1AGTR2DRD2TBXA2RPPARG | |
| SCHEMBL9195616 | 0.83 | AGTR1 (0.80) | AGTR1AGTR2PPARG | |
| SCHEMBL9198105 | 0.82 | AGTR1 (0.78) | AGTR1AGTR2DRD2TBXA2RPPARG | |
| SCHEMBL9087920 | 0.81 | AGTR1 (0.76) | AGTR1AGTR2DRD2TBXA2RPPARG | |
| SCHEMBL9201172 | 0.80 | DRD2 (0.78) | AGTR1AGTR2DRD2TBXA2RPPARG | |
| SCHEMBL9196687 | 0.80 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9123025 | 0.79 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9271577 | 0.77 | AGTR1 (0.80) | AGTR1AGTR2DRD2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399732-B1 | Benzimidazole derivatives | ZENECA LTD (GB) | 1995-07-26 | — | — | EP | disclosed |
| US-5171748-A | For hypertension, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-15 | — | — | US | disclosed |
| EP-0399732-A1 | Benzimidazole derivatives | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |