SCHEMBL9200980

SCHEMBL9200980

Cc1c(S(N)(=O)=O)c(C(F)(F)F)nn1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PROKR1 Q8TCW9 5/20 0.44
FPR2 P25090 4/20 0.44
CA1 P00915 8/20 0.42
CA2 P00918 8/20 0.42
CA12 O43570 3/20 0.40
CA4 P22748 3/20 0.40
CA6 P23280 3/20 0.40
CA5A P35218 3/20 0.40
CA7 P43166 3/20 0.40
CA9 Q16790 3/20 0.40
CA14 Q9ULX7 3/20 0.40
CA5B Q9Y2D0 3/20 0.40
CA3 P07451 2/20 0.40
CA13 Q8N1Q1 2/20 0.40
POLB P06746 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13184379 0.84 PROKR1 (0.45) PROKR1FPR2CA1CA2CA12
SCHEMBL8762829 0.82 PROKR1 (0.45) PROKR1FPR2CA1CA2POLB
Hydrochloric Acid SCHEMBL27293482 0.81 PROKR1 (0.43) PROKR1FPR2CA1CA2CA12
SCHEMBL3376273 0.75 TSHR (0.44) PROKR1FPR2CA1CA2CA12
SCHEMBL8560821 0.71 POLB (0.43) PROKR1FPR2POLBNPC1L3MBTL1
SCHEMBL9429829 0.71 POLB (0.36) PROKR1FPR2POLBNPC1HPGD
SCHEMBL764718 0.70 ALDH1A1 (0.36) PROKR1FPR2POLBNPC1L3MBTL1
SCHEMBL12124199 0.70 POLB (0.38) PROKR1FPR2POLBNPC1L3MBTL1
Formamide SCHEMBL5345806 0.69 POLB (0.36) PROKR1FPR2POLBNPC1L3MBTL1
SCHEMBL13184332 0.69 POLB (0.37) PROKR1FPR2POLBNPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7242637-A None JP disclosed
JP-H07242637-A SULFONYLPYRAZOLE COMPOUND NISSAN CHEM IND LTD 1995-09-19 JP disclosed
EP-0087780-B2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL IND LTD (JP) 1995-02-15 EP disclosed
US-4954164-A Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-04 US disclosed
EP-0087780-A2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1983-09-07 EP disclosed