Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194455 | 0.84 | SLC6A2 (0.63) | SLC6A2ROCK1MEN1NPC1RAB9A | |
| SCHEMBL9500230 | 0.84 | BCHE (0.43) | MEN1NPC1RAB9AKMT2AGRM2 | |
| SCHEMBL9194863 | 0.81 | SLC6A2 (0.65) | SLC6A2 | |
| Oxalic Acid SCHEMBL9196754 | 0.80 | SLC6A2 (0.57) | SLC6A2ROCK1MEN1NPC1RAB9A | |
| SCHEMBL9739947 | 0.80 | ROCK1 (0.43) | ROCK1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8845681 | 0.79 | BCHE (0.48) | SLC6A2 | |
| Hydrochloric Acid SCHEMBL8544423 | 0.79 | ROCK1 (0.42) | ROCK1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14977575 | 0.79 | NPC1 (0.50) | ROCK1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8845692 | 0.78 | BCHE (0.41) | SLC6A2 | |
| SCHEMBL7621050 | 0.74 | BCHE (0.51) | SLC6A2ROCK1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214058-A | Acetylcholinesterase inhibitors, treatment of senile dementia | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-05-25 | — | — | US | claimed |
| EP-0471296-B1 | 1-(Pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST ROUSSEL PHARMA (US) | 1995-11-08 | — | — | EP | disclosed |
| US-5214058-A | Acetylcholinesterase inhibitors, treatment of senile dementia | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0471296-A1 | 1-(Pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-02-19 | — | — | EP | disclosed |