Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.33 |
| ▸ | ITGAV | P06756 | 4/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845681 | 0.92 | BCHE (0.48) | BCHEACHESLC6A2ITGB3ITGAV | |
| SCHEMBL9201002 | 0.78 | SLC6A2 (0.43) | SLC6A2 | |
| SCHEMBL8845539 | 0.76 | SLC6A2 (0.56) | BCHEACHESLC6A2ITGB3ITGAV | |
| SCHEMBL8846194 | 0.76 | BCHE (0.62) | BCHEACHEFAAH | |
| SCHEMBL9194863 | 0.75 | SLC6A2 (0.65) | SLC6A2 | |
| SCHEMBL8845725 | 0.75 | SLC6A2 (0.54) | BCHEACHESLC6A2FAAHITGB3 | |
| SCHEMBL9198333 | 0.75 | TSHR (0.45) | — | |
| SCHEMBL9738851 | 0.75 | BCHE (0.50) | BCHEACHEFAAH | |
| Hydrochloric Acid SCHEMBL9671998 | 0.74 | BCHE (0.49) | BCHEACHEFAAH | |
| SCHEMBL9738706 | 0.74 | BCHE (0.47) | BCHEFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688816-A | COGNITION ACTIVATOR; ALZHEIMER'S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0471298-B1 | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST ROUSSEL PHARMA (US) | 1995-11-02 | — | — | EP | disclosed |
| US-5455245-A | Alzheimer*s disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5264442-A | For treating alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-11-23 | — | — | US | disclosed |
| EP-0471298-A1 | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-02-19 | — | — | EP | disclosed |