Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13663906 | 0.72 | BCHE (0.37) | BCHE | |
| SCHEMBL9198258 | 0.70 | KMT2A (0.31) | KMT2A | |
| SCHEMBL9210052 | 0.68 | KDM4C (0.33) | MEN1KMT2A | |
| SCHEMBL7610193 | 0.59 | SLC6A2 (0.66) | BCHE | |
| SCHEMBL7609242 | 0.59 | BCHE (0.42) | BCHE | |
| SCHEMBL9665183 | 0.59 | SLC6A2 (0.62) | BCHE | |
| Hydrochloric Acid SCHEMBL7643682 | 0.58 | BCHE (0.41) | BCHE | |
| SCHEMBL8860332 | 0.57 | BCHE (0.38) | BCHE | |
| SCHEMBL9381929 | 0.57 | BCHE (0.41) | BCHE | |
| Nerispirdine SCHEMBL3842518 | 0.57 | SLC6A2 (0.67) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415103-B1 | 2,3-Dihydro-1-(pyridinylamino)-indoles, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5296488-A | Method of using 2,3-dihydro-1-(pyridinylamino)-indoles as anticonvulsants and for the enhancement of memory | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-22 | — | — | US | disclosed |
| US-5179099-A | Analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-01-12 | — | — | US | disclosed |
| EP-0415103-A1 | 2,3-Dihydro-1-(pyridinylamino)-indoles, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-03-06 | — | — | EP | disclosed |