Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872029 | 0.71 | SLC6A2 (0.33) | KMT2ASLC6A2 | |
| SCHEMBL9201193 | 0.70 | BCHE (0.36) | KMT2A | |
| SCHEMBL9379716 | 0.66 | CYP19A1 (0.32) | KMT2ASLC6A2 | |
| SCHEMBL13663906 | 0.66 | BCHE (0.37) | SLC6A2 | |
| SCHEMBL9210052 | 0.66 | KDM4C (0.33) | KMT2A | |
| SCHEMBL9206194 | 0.64 | SLC6A2 (0.34) | SLC6A2 | |
| SCHEMBL26056119 | 0.62 | AOC1 (0.38) | KMT2ATLR8SLC6A2 | |
| SCHEMBL8872220 | 0.60 | LMNA (0.31) | — | |
| SCHEMBL9209495 | 0.60 | SLC6A2 (0.50) | SLC6A2 | |
| SCHEMBL9377108 | 0.58 | CYP19A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415103-B1 | 2,3-Dihydro-1-(pyridinylamino)-indoles, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5296488-A | Method of using 2,3-dihydro-1-(pyridinylamino)-indoles as anticonvulsants and for the enhancement of memory | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-22 | — | — | US | disclosed |
| US-5179099-A | Analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-01-12 | — | — | US | disclosed |
| EP-0415103-A1 | 2,3-Dihydro-1-(pyridinylamino)-indoles, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-03-06 | — | — | EP | disclosed |