Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201238 | 0.88 | CYP3A4 (0.46) | HSP90AA1NPSR1CYP3A4THRBCYP2C9 | |
| SCHEMBL9203098 | 0.86 | HSP90AA1 (0.51) | HSP90AA1NPSR1MAPTCYP19A1CYP3A4 | |
| SCHEMBL9198433 | 0.85 | CYP3A4 (0.45) | HSP90AA1NPSR1CYP19A1CYP3A4THRB | |
| SCHEMBL9201064 | 0.83 | ALDH1A1 (0.50) | HSP90AA1NPSR1MAPTCYP19A1CYP3A4 | |
| SCHEMBL9201132 | 0.80 | HSP90AA1 (0.38) | HSP90AA1NPSR1MAPTCYP19A1CYP3A4 | |
| SCHEMBL9195001 | 0.78 | HSP90AA1 (0.40) | HSP90AA1NPSR1MAPTCYP19A1CYP3A4 | |
| SCHEMBL10594715 | 0.75 | HSP90AA1 (0.36) | HSP90AA1NPSR1MAPTCYP19A1CYP3A4 | |
| SCHEMBL9202244 | 0.74 | CYP3A4 (0.58) | HSP90AA1MAPTCYP3A4THRBCYP2C9 | |
| SCHEMBL9200532 | 0.71 | CYP3A4 (0.42) | HSP90AA1CYP19A1CYP3A4THRBCYP2C9 | |
| SCHEMBL9314674 | 0.71 | CYP3A4 (0.44) | HSP90AA1NPSR1MAPTCYP19A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431968-B1 | Oxetane derivatives, their preparation and their use as anti-fungal or fungicidal agents | SANKYO CO (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5134152-A | 1,2,4-Triazole compounds | SANKYO COMPANY, LIMITED (JP) | 1992-07-28 | — | — | US | disclosed |
| EP-0431968-A1 | Oxetane derivatives, their preparation and their use as anti-fungal or fungicidal agents | Sankyo Company Limited (JP) | 1991-06-12 | — | — | EP | disclosed |