Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 11/20 | 0.54 |
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | TDO2 | P48775 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817825 | 0.87 | CTSB (0.63) | CTSBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18979856 | 0.86 | MAPT (0.55) | CTSBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9201355 | 0.84 | MAPT (0.52) | CTSBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27190087 | 0.84 | KDM4E (0.78) | CTSBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17597346 | 0.84 | KMT2A (0.70) | CTSBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL24715786 | 0.80 | MAPT (0.50) | CTSBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18979720 | 0.80 | ALDH1A1 (0.55) | CTSBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29777337 | 0.80 | MAPT (0.67) | CTSBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5188552 | 0.80 | MAPT (0.67) | CTSBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2204811 | 0.79 | HSP90AA1 (0.62) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664807-A1 | QUINOXALINEDIONE DERIVATIVES AS EAA ANTAGONISTS. | WARNER LAMBERT CO (US) | 1995-08-02 | — | — | EP | claimed |
| WO-1994009000-A1 | QUINOXALINEDIONE DERIVATIVES AS EAA ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1994-04-28 | — | — | WO | claimed |