Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201203 | 1.00 | MEN1 (0.52) | MEN1KMT2ACRHBPCRHR2APP | |
| SCHEMBL9198391 | 0.87 | CNR1 (0.35) | MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL9195083 | 0.85 | CNR1 (0.43) | KMT2A | |
| SCHEMBL9194746 | 0.85 | CNR1 (0.43) | KMT2A | |
| SCHEMBL9272274 | 0.85 | HDAC3 (0.40) | MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL9272277 | 0.85 | HDAC3 (0.40) | MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL9200548 | 0.83 | MTNR1A (0.41) | — | |
| SCHEMBL9200553 | 0.83 | MTNR1A (0.41) | — | |
| SCHEMBL9201122 | 0.82 | TDP1 (0.48) | MEN1KMT2A | |
| SCHEMBL9196217 | 0.82 | MEN1 (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |