Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004070 | 0.92 | — | — | |
| SCHEMBL987593 | 0.67 | ESR1 (0.38) | KCNH2ALDH1A1PTGS2ESR1ADRA2A | |
| SCHEMBL1286045 | 0.67 | ESR1 (0.38) | KCNH2ALDH1A1PTGS2ESR1ADRA2A | |
| SCHEMBL735087 | 0.67 | ESR1 (0.38) | KCNH2ALDH1A1PTGS2ESR1ADRA2A | |
| SCHEMBL1285757 | 0.67 | ESR1 (0.38) | KCNH2ALDH1A1PTGS2ESR1ADRA2A | |
| SCHEMBL16892538 | 0.67 | ESR1 (0.38) | KCNH2ALDH1A1PTGS2ESR1ADRA2A | |
| SCHEMBL19861696 | 0.67 | TBXAS1 (0.39) | KCNH2ALDH1A1TDP1L3MBTL1PTGS2 | |
| SCHEMBL16266833 | 0.67 | TBXAS1 (0.39) | KCNH2ALDH1A1TDP1L3MBTL1PTGS2 | |
| SCHEMBL21230535 | 0.67 | KCNH2 (0.38) | KCNH2ALDH1A1TDP1L3MBTL1PTGS2 | |
| SCHEMBL8923831 | 0.66 | ESR1 (0.45) | KCNH2ALDH1A1PTGS2ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214476-B | One class contains 4-methyl isophthalic acid, carboxamidine derivatives of 2,3-thiadiazoles and its production and use | NANKAI UNIVERSITY (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-103214476-A | Formamidine derivatives containing 4-methyl-1,2,3-thiadiazole, and preparation methods and uses | UNIV NANKAI | 2013-07-24 | — | — | CN | claimed |
| CN-103214476-B | One class contains 4-methyl isophthalic acid, carboxamidine derivatives of 2,3-thiadiazoles and its production and use | NANKAI UNIVERSITY (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-103214476-A | Formamidine derivatives containing 4-methyl-1,2,3-thiadiazole, and preparation methods and uses | UNIV NANKAI | 2013-07-24 | — | — | CN | disclosed |
| CN-1029227-C | Composition for denatured denaturation or protection agent for nerve cell and process for preparing benzene derivatives used for composition | OTSUKA PHARMA CO LTD (JP) | 1995-07-05 | — | — | CN | disclosed |
| EP-0382213-B1 | Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent | OTSUKA PHARMA CO LTD (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5053548-A | Containing hydroxy substituents; nervous system disorders | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| CN-1044807-A | Neurocyte sex change reparation or protective material are with composition and the preparation method that is used for the benzene derivative of said composition | OTSUKA PHARMA CO LTD (JP) | 1990-08-22 | — | — | CN | disclosed |
| EP-0382213-A2 | Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |