Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207070 | 0.93 | MAPK1 (0.50) | MAPK1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL9204220 | 0.82 | MAPK1 (0.56) | MAPK1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL9203361 | 0.81 | MAPK1 (0.58) | MAPK1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL9204042 | 0.80 | MAPK1 (0.53) | MAPK1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL9203559 | 0.76 | RAB9A (0.51) | MAPK1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL8930142 | 0.76 | MAPK1 (0.70) | MAPK1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL9205625 | 0.75 | MAPK1 (0.58) | MAPK1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL9198227 | 0.73 | MAPK1 (0.56) | MAPK1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL9197103 | 0.72 | KMT2A (0.51) | MAPK1HSD17B10RAB9AKMT2AMEN1 | |
| SCHEMBL9745316 | 0.71 | RAB9A (0.73) | MAPK1HSD17B10RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |