Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336186 | 0.78 | FABP7 (0.46) | FABP7FABP5MMP2MMP9MMP12 | |
| SCHEMBL24933203 | 0.73 | MEN1 (0.46) | SMN1; SMN2 | |
| SCHEMBL22519562 | 0.73 | MEN1 (0.46) | SMN1; SMN2 | |
| SCHEMBL9825628 | 0.73 | TGM2 (0.40) | TSHRLMNASMN1; SMN2 | |
| SCHEMBL13363847 | 0.73 | KMT2A (0.48) | TSHRTDP1LMNA | |
| SCHEMBL21961574 | 0.73 | TSHR (0.51) | FABP7FABP5TSHRTDP1MAPK1 | |
| SCHEMBL23485377 | 0.73 | TSHR (0.51) | FABP7FABP5TSHRTDP1MAPK1 | |
| SCHEMBL8189090 | 0.73 | KMT2A (0.48) | TSHRTDP1LMNA | |
| SCHEMBL10137745 | 0.73 | TSHR (0.51) | FABP7FABP5TSHRTDP1MAPK1 | |
| SCHEMBL1077276 | 0.73 | TSHR (0.51) | FABP7FABP5TSHRTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126587-B1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMA (JP) | 1995-04-19 | — | — | EP | disclosed |