SCHEMBL9201714

SCHEMBL9201714

CCOC(=O)c1c(S(N)(=O)=O)c(C)nn1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
KMT2A Q03164 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.40
STS P08842 1/20 0.40
MAPT P10636 2/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
KDM4E B2RXH2 3/20 0.39
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
MAPK1 P28482 3/20 0.38
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
FPR2 P25090 2/20 0.36
PROKR1 Q8TCW9 2/20 0.36
LMNA P02545 1/20 0.36
CA9 Q16790 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15353484 0.85 CA1 (0.47) ALDH1A1NPSR1MAPTCA1CA2
SCHEMBL9200764 0.84 HPGD (0.50) ALDH1A1NPSR1KMT2AL3MBTL1CA1
SCHEMBL10475093 0.81 ALDH1A1 (0.36) ALDH1A1NPSR1KMT2AL3MBTL1CA1
SCHEMBL9274977 0.79 KDM4E (0.40) ALDH1A1NPSR1L3MBTL1MAPTCA1
SCHEMBL11275010 0.78 ALDH1A1 (0.47) ALDH1A1KMT2AL3MBTL1MAPTKDM4E
SCHEMBL728450 0.77 KMT2A (0.50) ALDH1A1NPSR1KMT2AL3MBTL1MAPT
SCHEMBL9196806 0.76 ALDH1A1 (0.45) ALDH1A1NPSR1KMT2AL3MBTL1MAPT
SCHEMBL10578960 0.76 PDE4D (0.44) ALDH1A1NPSR1KMT2AL3MBTL1MAPT
SCHEMBL9208273 0.76 ALDH1A1 (0.46) ALDH1A1NPSR1KMT2AL3MBTL1MAPT
SCHEMBL23123200 0.75 ALDH1A1 (0.42) ALDH1A1NPSR1KMT2AL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0087780-B2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL IND LTD (JP) 1995-02-15 EP disclosed
US-4954164-A Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-04 US disclosed