SCHEMBL9200764

SCHEMBL9200764

COC(=O)c1c(S(N)(=O)=O)c(C)nn1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.50
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 3/20 0.50
HSD17B10 Q99714 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.40
CA1 P00915 6/20 0.37
CA2 P00918 6/20 0.37
CA9 Q16790 6/20 0.37
CA12 O43570 5/20 0.37
NPSR1 Q6W5P4 1/20 0.35
CA5A P35218 2/20 0.35
CA14 Q9ULX7 2/20 0.34
HTT P42858 1/20 0.34
CA3 P07451 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA7 P43166 1/20 0.34
CA13 Q8N1Q1 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9201714 0.84 ALDH1A1 (0.45) HPGDKDM4EALDH1A1HSD17B10L3MBTL1
SCHEMBL7813710 0.84 KDM4E (0.41) HPGDKDM4EALDH1A1HSD17B10L3MBTL1
SCHEMBL10475093 0.83 ALDH1A1 (0.36) HPGDKDM4EALDH1A1HSD17B10L3MBTL1
SCHEMBL9274977 0.81 KDM4E (0.40) HPGDKDM4EALDH1A1HSD17B10L3MBTL1
SCHEMBL9201767 0.80 KDM4E (0.41) HPGDKDM4EALDH1A1HSD17B10L3MBTL1
SCHEMBL9197543 0.80 KDM4E (0.47) HPGDKDM4EALDH1A1HSD17B10CA1
SCHEMBL15353484 0.79 CA1 (0.47) HPGDKDM4EALDH1A1HSD17B10CA1
SCHEMBL9200620 0.78 L3MBTL1 (0.36) HPGDKDM4EALDH1A1HSD17B10L3MBTL1
SCHEMBL9200671 0.77 KDM4E (0.37) HPGDKDM4EALDH1A1HSD17B10L3MBTL1
SCHEMBL19555815 0.76 KDM4E (0.41) HPGDKDM4EALDH1A1L3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0087780-B2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL IND LTD (JP) 1995-02-15 EP disclosed
US-4954164-A Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-04 US disclosed
EP-0087780-A2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1983-09-07 EP disclosed